test.json 8.1 KB

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  1. {
  2. "Locus": "ZFP36L2",
  3. "Update_Date": {
  4. "Year": 2022,
  5. "Month": 2,
  6. "Day": 2
  7. },
  8. "Location": "2p21",
  9. "Summary": "This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq, Jul 2008]",
  10. "Genomic_Position": {
  11. "Accession": "NC_000002",
  12. "Positions": {
  13. "from": 43222401,
  14. "to": 43226605,
  15. "strand": "minus"
  16. }
  17. },
  18. "Gene_Ontology": {
  19. "Functions": [{
  20. "ID": 3723,
  21. "Pre_Text": "enables",
  22. "Anchor": "RNA binding"
  23. }, {
  24. "ID": 35925,
  25. "Pre_Text": "enables",
  26. "Anchor": "mRNA 3'-UTR AU-rich region binding"
  27. }, {
  28. "ID": 46872,
  29. "Pre_Text": "enables",
  30. "Anchor": "metal ion binding"
  31. }, {
  32. "ID": 5515,
  33. "Pre_Text": "enables",
  34. "Anchor": "protein binding"
  35. }],
  36. "Processes": [{
  37. "ID": 61158,
  38. "Pre_Text": "involved_in",
  39. "Anchor": "3'-UTR-mediated mRNA destabilization"
  40. }, {
  41. "ID": 61158,
  42. "Pre_Text": "involved_in",
  43. "Anchor": "3'-UTR-mediated mRNA destabilization"
  44. }, {
  45. "ID": 70371,
  46. "Pre_Text": "involved_in",
  47. "Anchor": "ERK1 and ERK2 cascade"
  48. }, {
  49. "ID": 33077,
  50. "Pre_Text": "involved_in",
  51. "Anchor": "T cell differentiation in thymus"
  52. }, {
  53. "ID": 71364,
  54. "Pre_Text": "involved_in",
  55. "Anchor": "cellular response to epidermal growth factor stimulus"
  56. }, {
  57. "ID": 44344,
  58. "Pre_Text": "involved_in",
  59. "Anchor": "cellular response to fibroblast growth factor stimulus"
  60. }, {
  61. "ID": 71385,
  62. "Pre_Text": "involved_in",
  63. "Anchor": "cellular response to glucocorticoid stimulus"
  64. }, {
  65. "ID": 97011,
  66. "Pre_Text": "involved_in",
  67. "Anchor": "cellular response to granulocyte macrophage colony-stimulating factor stimulus"
  68. }, {
  69. "ID": 71560,
  70. "Pre_Text": "involved_in",
  71. "Anchor": "cellular response to transforming growth factor beta stimulus"
  72. }, {
  73. "ID": 71356,
  74. "Pre_Text": "involved_in",
  75. "Anchor": "cellular response to tumor necrosis factor"
  76. }, {
  77. "ID": 60216,
  78. "Pre_Text": "involved_in",
  79. "Anchor": "definitive hemopoiesis"
  80. }, {
  81. "ID": 30097,
  82. "Pre_Text": "involved_in",
  83. "Anchor": "hemopoiesis"
  84. }, {
  85. "ID": 6402,
  86. "Pre_Text": "involved_in",
  87. "Anchor": "mRNA catabolic process"
  88. }, {
  89. "ID": 45599,
  90. "Pre_Text": "involved_in",
  91. "Anchor": "negative regulation of fat cell differentiation"
  92. }, {
  93. "ID": 1901991,
  94. "Pre_Text": "involved_in",
  95. "Anchor": "negative regulation of mitotic cell cycle phase transition"
  96. }, {
  97. "ID": 2000737,
  98. "Pre_Text": "involved_in",
  99. "Anchor": "negative regulation of stem cell differentiation"
  100. }, {
  101. "ID": 288,
  102. "Pre_Text": "involved_in",
  103. "Anchor": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"
  104. }, {
  105. "ID": 1900153,
  106. "Pre_Text": "involved_in",
  107. "Anchor": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"
  108. }, {
  109. "ID": 45577,
  110. "Pre_Text": "involved_in",
  111. "Anchor": "regulation of B cell differentiation"
  112. }, {
  113. "ID": 43488,
  114. "Pre_Text": "involved_in",
  115. "Anchor": "regulation of mRNA stability"
  116. }, {
  117. "ID": 43488,
  118. "Pre_Text": "involved_in",
  119. "Anchor": "regulation of mRNA stability"
  120. }, {
  121. "ID": 9611,
  122. "Pre_Text": "involved_in",
  123. "Anchor": "response to wounding"
  124. }, {
  125. "ID": 48103,
  126. "Pre_Text": "involved_in",
  127. "Anchor": "somatic stem cell division"
  128. }, {
  129. "ID": 35019,
  130. "Pre_Text": "involved_in",
  131. "Anchor": "somatic stem cell population maintenance"
  132. }],
  133. "Components": [{
  134. "ID": 5737,
  135. "Pre_Text": "located_in",
  136. "Anchor": "cytoplasm"
  137. }, {
  138. "ID": 5634,
  139. "Pre_Text": "located_in",
  140. "Anchor": "nucleus"
  141. }]
  142. },
  143. "Transcript": {
  144. "Accession": "NM_006887",
  145. "Exon_Count": 2
  146. },
  147. "Products": {
  148. "Accession": "NP_008818",
  149. "Domains": [{
  150. "DB": "CDD",
  151. "ID": 279036,
  152. "Anchor": "pfam00642: zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)",
  153. "Location": ["Location: 154 - 179", "Location: 192 - 216"]
  154. }, {
  155. "DB": "CDD",
  156. "ID": 282420,
  157. "Anchor": "pfam04553: Tis11B_N; Tis11B like protein, N terminus",
  158. "Location": "Location: 3 - 131"
  159. }]
  160. },
  161. "Biblio_PMID": [22658674, 20506496, 25106868, 25106868, 25106868, 25106868, 20166898, 20166898, 20166898, 20166898, 20166898, 20166898, 25106868, 27182009, 34333017, 33590411, 32655569, 31048690, 29518627, 29426877, 28860350, 27862697, 27182009, 25809263, 25106868, 22658674, 21873635, 21509594, 21278925, 21151128, 21109922, 20506496, 20166898, 19274049, 17172869, 15489334, 14981510, 14604009, 12477932, 8889549, 8545129, 7835719, 21151128, 34333017, 33590411, 32655569, 29426877, 31048690, 29518627, 28860350, 27862697, 25809263, 21278925, 21109922, 21509594, 20506496, 14981510, 14604009, 17172869, 33961781, 33961781, 28514442, 26972000, 33961781, 33961781, 29449217, 33961781, 29449217, 33961781, 29449217, 33961781, 29449217, 24255178, 34079125, 32694731, 29395067, 29395067, 32694731, 31527615, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 29449217, 17979178, 29449217, 29509190, 29053956, 27173435, 26496610, 26496610, 26496610, 26673895, 21145461]
  162. }